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（最終更新日：2023-07-10 11:39:58）   タカイ　ケンジ   TAKAI KENJI   高井憲治    所属   医学部医学科 免疫学・病害動物学    職種   客員教授

■ 学術雑誌 1. 総説・解説　 Innate immune responses in Behçet disease and relapsing 2023/06 2. 原著　 Nicotine treatment regulates PD-L1 and PD-L2 expression via inhibition of Akt pathway in HER2-type breast cancer cells. 2022/01 3. 原著　 Updated distribution of anopheline mosquitoes in Hokkaido, Japan, and the first evidence of Anopheles belenrae in Japan. 2021/09 4. 総説・解説　 神奈川県とダニ媒介感染症：ダニ媒介感染症の現状と隣接県との関連について 2021/07 5. 原著　 Defective Reelin/Dab1 signaling pathways associated with disturbed hippocampus development of homozygous yotari mice. 2021/04 6. 原著　 Dementia model mice exhibited improvements of neuropsychiatric symptoms as well as cognitive dysfunctions with neural cell transplantation 2021/04 7. 原著　 Female dominance of both spatial cognitive dysfunction and neuropsychiatric symptoms in a mouse model of Alzheimer's disease. 2021/04 8. 症例報告　 Patient consultation in the Department of Immunology and Medical Zoology at St. Marianna University School of Medicine between 2001-2019 with an interest in parasitic diseases in Japan. J. St. Marianna Univ 2021/02 9. 原著　 Interaction between SDF1 and CXCR4 promotes photoreceptor differentiation via upregulation of NFkB pathway signalling activity in Pax6 gene transfected photoreceptor precursors 2020/01 10. 原著　 Insecticide-impregnated net originally invented to control malaria vectors can be used to control other arthropod pests 2019/12 11. 原著　 Transplantation of Human iPS Cell-Derived Neural Cells with an Artificial Nerve Conduit Leads to Cellular Retention in the Transplanted Area and Improves Motor Function in a Mouse Spinal Cord Injury Model 2019/12 12. 原著　 Relative abundance of Megamonas hypermegale and Butyrivibrio species decreased in the intestine and its possible association with the T cell aberration by metabolite alteration in patients with Behcet's disease. 2019/01 13. 原著　 Roles of Reelin/Disabled1 pathway on functional recovery of hemiplegic mice after neural cell transplantation; Reelin promotes migration toward motor cortex and maturation to motoneurons of neural grafts. 2019 14. 原著　 Efficacy of a novel mixture of substances derived from food and food additives for controlling Dermanyssus gallinae (Mesostigmata: Dermanyssidae). 2018/09 15. 原著　 Propionate-producing bacteria in the intestine may associate with skewed responses of IL10-producing regulatory T cells in patients with relapsing polychondritis. 2018/09 16. 総説・解説　 Cellular and Molecular Mechanisms Governing Functional Recovery of Dementia Mice after Neuronal cell Transplantation. 2018/01 17. 原著　 Neuronal cell sheet of cortical motor neuron phenotype derived from human iPS cells. 2017/08 18. 原著　 Bifidobacteria Abundance-Featured Gut Microbiota Compositional Change in Patients with Behcet's Disease 2016/04 19. 原著　 Possible association of proinflammatory cytokines including IL1β and TNFα with enhanced Th17 cell differentiation in patients with Behcet's disease. 2016 20. 原著　 Cellular and molecular mechanisms of the restoration of human APP transgenic mouse cognitive dysfunction after transplant of human iPS cell-derived neural cells. 2015/09 21. 原著　 Induction of neural cells with spinal motoneuron phenotype from human iPS cells and the transplantation to totally transected spinal cords in mice. 2015/05 22. 原著　 Possible association of proinflammatory cytokines including IL1β and TNFα with enhanced Th17 cell differentiation in patients with Behcet's disease 2015/05 23. 原著　 Generation of Retinal Progenitor Cell Sheets which Differentiate into Rhodopsin Positive Photoreceptors from Mouse iPS Cell Derived Retinal Progenitor Cell Clones. 2015/02 24. 原著　 Pax7 Gene Induction Rapidly Regulates Myocyte Homeostasis in Human Induced Pluripotent Stem (iPS) Cells. 2014/12 25. 原著　 Human iPS Cell Derived Neurons with Cortical Motor Neuron Phenotype are Relevant for Functional Recovery of Hemiplegic Mice with Injured Motor Cortex. 2013/12 26. 原著　 IGFII/Akt Signaling Regulates Myocyte Homeostasis in Human Induced Pluripotent Stem (iPS) Cells. 2013/12 27. 原著　 Transplantation of Motor Neurons Derived from Human iPS Cells into Total Transection Model of Spinal Cord Injury in Mice. 2013/12 28. 原著　 Restoration of spatial memory dysfunction of human APP transgenic mice by transplantation of neurons derived from human iPS cells. 2013 29. 症例報告　 アニサキス症の2例Pseudoterranova azarasi幼虫感染例と糞便内に幼虫の排泄をみた例 2012/12 30. 原著　 Skewed TGFβ/Smad signaling pathway of T cells in patients with Behçet's disease. 2012/05 31. 原著　 Excessive CD4+ T cells co-expressing interleukin-17 and interferon-γ in patients with Behçet's disease. 2012/04 5件表示 全件表示(31件)

■ 学会発表 1. 腫瘍免疫での免疫チェックポイントに対するニコチンの影響 （口頭発表，一般） 2021/09 2. 全切断脊髄損傷モデルへの人工神経導管併用神経幹細胞移植の治療効果 （ポスター，一般） 2020/10/15 3. 完全離断脊髄損傷マウスモデルに対する神経再生誘導チューブ併用ヒトiPS細胞由来神経幹/前駆細胞移植の検討 （ポスター，一般） 2019/10/17 4. MOTOR FUNCTION RECOVERY IN HEMIPLEGIC MICE AFTER NEURAL STEM / PROGENITOR CELLS TRANSPLANTATION （ポスター，一般） 2019/06/26 5. 認知症モデルマウスを用いたヒトiPS由来神経細胞移植による認知機能改善における心理症状の評価と関連 （口頭発表，一般） 2019/05/15 6. Neural regeneration after transplantation of Neuronal cell sheet of cortical motor neuron phenotype （ポスター，一般） 2018/09/06 7. A STUDY ON THE IMPORTANCE OF REGENERATION OF GABAERGIC NEURONS IN RESTORING COGNITIVE FUNCTION BY HIPS DERIVED NEURAL CELL TRANSPLANTATION TO DEMENTIA MODEL MICE （ポスター，一般） 2018/06/20 8. NEURAL REGENERATION MECHANISMS IN TRANSPLANTATION OF NEURONAL CELLS DERIVED FROM HUMAN INDUCED PLURIPOTENT STEM CELLS WITH THE EFFECT OF THEIR PARACRINE SECRETION （ポスター，一般） 2018/06/20 9. Reelin Signal Activation is Associated With Motor Function Recovery in the Neuron Transplantation of Hemiplegic Mice. （ポスター，一般） 2018/01/16 10. 脳損傷マウスに対する幹細胞由来神経細胞移植による神経再生 （ポスター，一般） 2016/12/02 11. RESTORATION OF HUMAN APP TRANSGENIC MOUSE COGNITIVE DYSFUNCTION AFTER TRANSPLANT OF HUMAN IPS CELL-DERIVED NEURAL STEM/PRECURSOR CELLS （ポスター，一般） 2016/06/25 12. ヒトiPS細胞を用いた骨格筋細胞への分化誘導 （ポスター，一般） 2015/10/22 13. Human iPS derived neural stem/precursor improved spatial memory learning of dementia model mice. （ポスター，一般） 2015/06/25 14. ヒトiPS細胞から誘導した神経細胞移植による認知機能の改善とそのメカニズムについての検討 （ポスター，一般） 2015/06/05 15. ヒトiPS由来神経細胞移植による空間記憶能の改善と改善メカニズムについての検討. （ポスター，一般） 2015/03/20 16. 脊髄全切断マウスにおけるヒトiPS細胞由来神経細胞移植後脊髄再生メカニズム （口頭発表，一般） 2014/10/09 17. Restoration of spatial memory dysfunction of human APP transgenic mice by transplantation of neuronal precursors derived from hIPS cells. （ポスター，一般） 2014/06/19 18. ヒトiPS細胞から誘導した神経細胞移植による空間機能の改善と改善メカニズムの検討. （ポスター，一般） 2014/03 19. ヒトiPS細胞由来神経前駆細胞の運動神経分化誘導と脳損傷モデルマウスへの移植応用 （口頭発表，一般） 2013/07/05 20. Differentiation of cholinergic neurons from hiPS cells and restration of cognitive function by their transplantation in mice with dementia. （ポスター，一般） 2013/06 21. ヒトinduced pluripotent stem cell(hiPS)細胞からの皮質運動神経分化誘導. （ポスター，一般） 2013/03 22. ヒトiPS細胞由来神経細胞移植による認知症モデルマウスの認知機能改善効果の検討. （ポスター，一般） 2013/03 23. ヒト誘導多能性幹細胞の運動神経分化誘導と脳卒中モデルマウスへの移植応用 （ポスター，一般） 2012/10/19 24. Experimental transplantation of human iPS cells derived neural cells in a mouse model of hemiplegia. （ポスター，一般） 2012/06 25. Transplantation of neural cells derived from human ips cells into an alzheimer's disease model. （ポスター，一般） 2012/06 26. ヒトiPS細胞の神経分化誘導と片麻痺モデルマウスへの移植. （ポスター，一般） 2012/06 27. ヒトiPS細胞由来神経細胞のアルツハイマー病モデルへの移植実験. （ポスター，一般） 2012/06 5件表示 全件表示(27件)