イマイ ナオヒコ   IMAI NAOHIKO
  今井直彦
   所属   医学部医学科 腎臓・高血圧内科
   職種   准教授
論文種別 症例報告
言語種別 英語
査読の有無 査読なし
表題 Cutaneous cholesterol embolization syndrome.
掲載誌名 正式名:Indian journal of dermatology, venereology and leprology
略  称:Indian J Dermatol Venereol Leprol
ISSNコード:03786323/09733922
巻・号・頁 81(4),388頁
著者・共著者 ◎Imai N, Zamami R, Kimura K.
担当区分 筆頭著者,責任著者
発行年月 2015/07
概要 A 67-year-old man with type 2 diabetes mellitus underwent percutaneous coronary intervention. Six weeks later, bluish reticulated patches were observed on the tips of his toes and an ulcer was noted on his right toe [Figure 1]a. Laboratory tests showed eosinophilia, an elevated serum creatinine level and an elevated lactate dehydrogenase level. Skin biopsy showed the presence of cholesterol clefts in the lumen of a vessel [Figure 1]b]. His kidney function continued to deteriorate and reached end-stage renal disease in 3 months. Cholesterol embolization syndrome is caused by embolization of cholesterol crystals and is commonly associated with iatrogenic manipulations. Skin biopsy is diagnostic and the needle-shaped spaces noted within the lumen of arterioles of the affected skin are characteristic.
DOI 10.4103/0378-6323.158664
PMID 26087104