研究者情報

トミタ　ハヤト   TOMITA HAYATO   冨田隼人    所属   医学部医学科 放射線診断・ＩＶＲ学    職種   講師
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Achieving high spatial and temporal resolution with perfusion MRI in the head and neck region using golden-angle radial sampling
掲載誌名	正式名：European Radiology
掲載区分	国外
巻・号・頁	31(4),2263-2271頁
著者・共著者	Andrea Tomppert, Wolfgang Wuest, Marco Wiesmueller, Rafael Heiss, Markus Kopp, Armin M Nagel, Hayato Tomita, Christian Meixner, Michael Uder, Matthias Stefan May
発行年月	2020/09
概要	Objectives: Conventional perfusion-weighted MRI sequences often provide poor spatial or temporal resolution. We aimed to overcome this problem in head and neck protocols using a golden-angle radial sparse parallel (GRASP) sequence. Methods: We prospectively included 58 patients for examination on a 3.0-T MRI using a study protocol. GRASP (A) was applied to a volumetric interpolated breath-hold examination (VIBE) with 135 reconstructed pictures and high temporal (2.5 s) and spatial resolution (0.94 × 0.94 × 3.00 mm). Additional sequences of matching temporal resolution (B: 2.5 s, 1.88 × 1.88 × 3.00 mm), with a compromise between temporal and spatial resolution (C: 7.0 s, 1.30 × 1.30 × 3.00 mm) and with matching spatial resolution (D: 145 s, 0.94 × 0.94 × 3.00 mm), were subsequently without GRASP. Instant inline-image reconstructions (E) provided one additional series of averaged contrast information throughout the entire acquisition duration of A. Overall diagnostic image quality, edge sharpness and contrast of soft tissues, vessels and lesions were subjectively rated using 5-point Likert scales. Objective image quality was measured as contrast-to-noise ratio in D and E. Results: Overall, the anatomic and pathologic image quality was substantially better with the GRASP sequence for the temporally (A/B/C, all p < 0.001) and spatially resolved comparisons (D/E, all p < 0.002 except lesion edge sharpness with p = 0.291). Image artefacts were also less likely to occur with GRASP. Differences in motion, aliasing and truncation were mainly significant, but pulsation and fat suppression were comparable. In addition, the contrast-to-noise ratio of E was significantly better than that of D (pD-E < 0.001). Conclusions: High temporal and spatial resolution can be obtained synchronously using a GRASP-VIBE technique for perfusion evaluation in head and neck MRI.